da molecularpost | Mag 27, 2022 | Biologia Molecolare, Cancer, Intestine, Therapeutic perspective
Defining Distinct Colorectal Cancer Models: New Therapeutic Perspectives Figure 1 – Investigation of molecular differences and immune microenvironment in MSS and MSI-H CRCs performing in silico, in vitro and in vivo experiments. Abstract In the...
da molecularpost | Giu 5, 2019 | Biologia Molecolare, Therapeutic perspective
A new potential therapeutic target for treating fragile X syndrome Abstract Fragile X Syndrome (FXS) is one of the most important genetic cause of cognitive disabilities and autism. The authors analyzed more specifically all the chromatin-associated proteins regulated...
da molecularpost | Mag 10, 2018 | Biologia Molecolare, Cancer, Therapeutic perspective
Anti-cancer therapy: resistance to DNA damage in renewable tissues At the base of resistance to DNA damage in renewable tissues there is an increment of EZH2 levels, whose turnover is controlled by p53 and MDM2 proteins. In this way, are uncovered the epigenetic...