da molecularpost | Giu 14, 2023 | Biologia Molecolare, Intestine, Organoids, Regeneration
Controlling intestinal organoid regeneration with retinoic acid and RXR inhibition Fig. 1 – RXR is a homing mechanism to exit regenerative state and its inhibition leads to regenerative phenotype; retinoic acid provides tissue-specificity [Created with...
da molecularpost | Mag 26, 2023 | Biologia Molecolare, Intestine, Organoids
New Culture Condition for Human Intestinal Organoids allowing Secretory Cells appearance and Self-Renewal Capacity maintenance Figure 1. Schematic comparison between IF-cultured organoids and those cultured with the p38i-medium, highlighting the IF-medium advantages....
da molecularpost | Mag 27, 2022 | Biologia Molecolare, Cancer, Intestine, Therapeutic perspective
Defining Distinct Colorectal Cancer Models: New Therapeutic Perspectives Figure 1 – Investigation of molecular differences and immune microenvironment in MSS and MSI-H CRCs performing in silico, in vitro and in vivo experiments. Abstract In the...
da molecularpost | Mag 27, 2022 | Aging, Biologia Molecolare, Cancer, Intestine
Braf mutation and aging relationship in colon cancer Fig. 1 – Malignant transformation of SSLs. Abstract Sessile Serrated Lesions (SSLs) are common colonic lesions present in patients of all ages. In their progression, these lesions acquire extensive DNA...