da molecularpost | Mag 27, 2022 | Aging, Biologia Molecolare, Cancer, Intestine
Braf mutation and aging relationship in colon cancer Fig. 1 – Malignant transformation of SSLs. Abstract Sessile Serrated Lesions (SSLs) are common colonic lesions present in patients of all ages. In their progression, these lesions acquire extensive DNA...
da molecularpost | Giu 4, 2021 | Biologia Molecolare
How what we eat influences epigenetics: a study on methionine restriction Abstract Chromatin methylation has been shown to be particularly susceptible to diet-related stresses. SAM depletion induced by methionine restriction elicits a metabolic response that is...
da molecularpost | Giu 28, 2020 | Biologia Molecolare
Epigenetic regulation of bivalent chromatin in cranial neural crest cells Abstract The epigenetic regulation of cranial neural crest cells is fundamental to maintain positional plasticity through migration and to have a normal craniofacial development. Bivalent...
da molecularpost | Giu 8, 2019 | Biologia Molecolare
The necessity to further comprehend the heterogeneity between single cells, as well as the ability to study the cell lineage trees, become clear with the progress in studying of the epigenome, genome, and transcriptome. A major obstacle in understanding the individual...
da molecularpost | Giu 6, 2019 | Biologia Molecolare
Minhee Park, Ahmad S. Khalil, and their collaborators, at the University of Boston, studied a synthetic method capable to regulate epigenetic modification in humans cells (HEK293FT)[1]. This method was based on the introduction of the modification m6A...