The Turin’s News and Views of Scientific Journals Articles

Pangenome: a novel frontier for genetics

Authors

F. Bianciot & C. M. Scarsoglio

Deep learning models to design synthetic enhancers

Authors

A. Castino & A. Maggiora & M. Rossi

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2024

Plasma proteome: the new predictor of aging and disease

Like father, like son: how signatures can be inherited

p300/CBP-dependent enhancer’s dynamic activation

The human DNA methylation atlas: a new tool to study our tissues

Deep learning models to design synthetic enhancers

Sei: a new framework based on a deep learning model for deciphering human genetics

H3K36me: “The last stronghold” of cell identity

Alu-derived (SIRLOIN) Elements Promote Nuclear Localization of Long Noncoding RNAs and mRNAs in Human Cells

DNA structures drive CTCF binding and cell differentiation

Negative correlation between DNA methylation and maximum lifespan in mammals

Compatibility or specificity? The interaction between enhancers and promoters in human

Understanding intratumoral heterogeneity to defeat cancer

Pangenome: a novel frontier for genetics

Epigenetic modifications induce premature aging in mammals

Investigatin G-Quadruplexes with G4Access: A new frontier in Genomic Research

RNA polymerase II elongation speed: a key to aging and longevity

Up to 2023

Mechanisms involved in Dex-induced transcription

DNA sequence and shape signatures collaborate in selecting different homeodomain transcription factor complexes

The level of expression of long noncoding RNAs in mammalian Genome and molecular functions

Disordered regions in transcription factors lead to short-order binding

A New Study to Explain Intestinal Stem Cell Regeneration

Resistance mechanism of EGFR-mutant non-small cell lung cancer mediated by YAP

Is the analysis of liquid liquid phase separated chromatin useful to study in vitro the complex in vivo chromatin organization?

Sox2 guides R-loops to drive cellular reprogramming to pluripotency

Slide-DNA-seq: a novel technique to study cancer heterogeneity

Can Fluctuating Methylation Clocks track stem cell dynamics?

Braf mutation and aging relationship in colon cancer

Defining Distinct Colorectal Cancer Models: New Therapeutic Perspectives

A potential lncRNA-based cancer algorithm

Liver organoids: characteristics and future perspectives

Stable Relationship between Two Cell

Dynamic Enhancer DNA Methylation as Basis for Transcriptional and Cellular Heterogeneity of ESCs

An innovative non-linear alignment algorithm to compare non-coding RNAs

Can human heart regenerate? A new possible strategy

A single-cell survey of the small intestinal epithelium

Identification of cells capable of regenerating damaged intestine: revival stem cells

Promising models to study Down syndrome

How epigenetic modifications drive programmed genome rearrangement in Tetrahymena thermophila

Immune cells drive differentiation of intestinal stem cells

How what we eat influences epigenetics: a study on methionine restriction

Possible upstream regulators of DNA demethylating enzymes in the central nervous system

scRNA-seq reveals a high reproducibility of the brain’s organoids: a valuable organoid model for studying human neurological diseases?

Heterogeneity of Oligodendrocyte cell lineage

The importance of non-coding variants in neuropsychiatric disorders

LDHA in autoinflammatory diseases

Molecular aspects of the interaction between host epigenome, gut microbiota and diet

The quest for glucose tumor cells vs T cells

Histone demethylase JMJD1C is phosphorilated by mTOR to activate de novo lipogenesis

Metabolic adaptation to diet: the role of promoter-enhancer interactions

Cellular acetyl-CoA metabolism is related to memory formation in the hippocampus

Single-cell genome-wide bisulfite sequencing (scBS-seq): a promising strategy to investigate the DNA methylome

Investigation of HDAC inhibitors action on metabolism using sci-Plex

Relationships between DNA methylation, chromatin accessibility and gene expression studied through ATAC-Me

A new method to analyze both RNA and proteins

Single-cell ChIP seq reveals cell subpopulations defined by chromatin state

A new assay that allows to discriminate cellular identity from a heterogeneous population

Epigenetic regulation of bivalent chromatin in cranial neural crest cells

DOT1L affects neuronal layer identity by influencing transcriptional programs

RbAp48: The Memory Gene

The duodenal cell population-specific methylome of celiac disease

Could an abiotic material mimic restriction enzymes?

Stella’s role in women’s fertility

scCAT-seq: a breakthrough into multi-omics layers investigation at single-cell level

Could CRISPR-CAS9 be a new strategy for the treatment of deafness?

G-Quadruplex as targets for Antimalaric Drugs

Epigenetic modifications: building a synthetic propagation system in human cells

A new function for sleep

Channelling the power of evolution for the synthesis of a new world

A new age for Synthetic Biology: L-SCRaMbLE, or, how to shuffle genome with light

Industrial application of a new optogenetic gene circuit: OptoEXP-OptoINVRT

Do you know the phenomenon of coral reefs bleaching?

An epygenetic way to contrast aging

Stem cells can trim their telomeres – and for good reasons too: here is how and why they do it

A new weapon to eradicate malaria

Methylome: tumoral ID

The lone virus dies but the pack survives

Biomarkers for adolescent idiopathic scoliosis

The New Generation of Biosurfactants: Potential Applications of Rhamnolipids

Does skeletal muscle have an epigenetic memory?

Did you know that arsenic influences long-term memory?

CRISPR-Cas9: a new prospective for Duchenne muscular dystrophy treatment

A new ternary molecular complex in Aortic thoracic aneurism cells dysfunction

A new therapeutic strategy for Neuroblastoma

Chromatin interactions in-situ analysis by CAPTURE

Bad news for HIV

The role of SUV39H1 in CD8+ T cell differentiation

CRISPR-Cpf1 assisted genome editing of Corynebacterium glutamicum

Reprogramming to Pluripotency Through
CRISPR-based Chromatin Remodeling

Bioenergetic regulation and neuronal differentiation NaBt mediated

Rheumatoid Arthritis: Epigenetic factors

 

CRISPR/Cas9 – mediated genome editing: a promising strategy to treat haemophilia B in newborn mice

 

Data driven approach to auxin transcriptomic response of Arabidopsis thaliana root cells

Gapmer Antisense Oligonucleotides: a turning point in the treatment of Ullrich Congenital Muscular Dystrophy?

 

Obesity influences Muscle Stem Cells

 

Genome-Wide DNA Methylation Profiling Reveals Epigenetic Changes in the Rat Nucleus Accumbens Associated with Cross-Generational Effects of Adolescent THC Exposure

Anti-cancer therapy: resistance to DNA damage in renewable tissues

A new potential therapeutic target for treating fragile X syndrome

Sars-CoV2 can integrate into genome thanks to LINE1

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